Characterization of Patients with Stromal Gastrointestinal Tumors in Arnaldo Milián Castro Clinical-Surgical Hospital

Abstract

Gastrointestinal stromal tumor is the most frequent mesenchymal neoplasm in the digestive tract, its diagnosis and treatment is still controversial because it is infrequent.

Objective: To characterize the patients with gastrointestinal stromal tumors treated in our service.

Methods: A longitudinal descriptive observational study was carried out in patients with gastrointestinal stromal tumors treated in the surgery service of the “Arnaldo Milián Castro” Clinical-Surgical Hospital from 2015 to 2018. The sample consisted of 17 patients.

Results: Female patients between 60 and 69 years old (35.3%) predominated (58.82%). Abdominal pain as the most frequent symptom (58.82%). Tumors (47.1%) measured more than 10 cm, spindle cell cellularity (58.8%), mitotic index less than 5 (70.6%), and no infiltrative growth pattern (70.6%). Metastasis absent in (82.4%). Present with equal frequency in the stomach and small intestine (N = 8), the presence of low and high aggressive behavior (35.3%) was the same. The markers CD.117 (41.2%) and CD.34 (35.3%) predominated. Segmental recession of the small intestine with end-to-end anastomosis was the most widely used surgical technique (35.3%).

Conclusions: Despite being mostly large and found in high portions of the digestive tract, many presented a low mitotic index, however, a considerable group presented aggressive behavior. Although it is true that almost all the patients were discharged alive, there is a lack of follow-up at the center, which would be interesting to evaluate in future studies.