TNM classification in lung cancer. Changes in the 9th edition.
Abstract
Background: the TNM classification was created with the objective of anatomically classifying cancer and offering prognostic and therapeutic guidance. Objectives: to perform an analysis of the TNM classifications for lung location, as well as the changes in the new classification. Methods: a search was carried out in the Scopus, Medline, Cochrane, Hinari and Redalyc databases using the descriptors: TNM, evolution, prognosis, essential TNM. Results: the main modifications of the TNM are related to tumor size, nodal stations and metastases. Molecular studies, liquid biopsy results and residual disease are prognostic factors to take into account in the overall survival of lung cancer. Conclusions: the TNM classification has evolved with medical knowledge. The new classification includes changes in the descriptor N and M. The molecular and genetic elements cannot be measured homogeneously, which means they are kept under review.
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